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SynCardia Systems, Inc.

Eliminate the Source of Heart Failure

Since 1990, the supply of donor hearts has been flat, and in some cases has declined, while heart failure continues to escalate. As demand for donor hearts outpaces supply more and more patients will need a bridge to a donor heart transplant (BTT).

The SynCardia Total Artificial Heart as a bridge to transplant is the standard of care for treating patients with end-stage biventricular heart failure. The key is to implant the SynCardia Total Artificial Heart before the patient’s vital organs and body suffer irreparable damage from low blood flow caused by the dying ventricles of the native heart.

Since 1990, the supply of donor hearts has been flat, and in some cases has declined, while heart failure has continued to escalate. As demand for donor hearts continues to grow, more patients will need a bridge to donor heart transplant (BTT).


 The SynCardia Total Artificial Heart

  • Like a heart transplant, the SynCardia Heart replaces the two native ventricles and four heart valves, which eliminates the source of heart failure.
  • Unlike a donor heart, the SynCardia Heart
    • is quickly available for implant at over 100 SynCardia Certified Centers worldwide
    • does not require expensive, immunosuppressant medications, which eventually cause subsequent complications
    • provides consistent quality, reliable performance and exact sizes: 70cc and 50cc TAH-ts.

Implanting the Total Artificial Heart eliminates

Failing Ventricles*

Malfunctioning Heart Valves*

  • Patients receive four new valves that have never failed in the SynCardia TAH-t. This eliminates the need for surgery to repair or replace malfunctioning native heart valves.

Arrhythmias and Other Electrical Problems*

  • The SynCardia Heart is powered by precisely calibrated pulses of air, so electrical complications are eliminated, as is the need for pacemakers or defibrillators.

Donor Heart Rejection

  • Graft failure is the leading cause of donor heart rejection. The SynCardia Heart is the only approved long-term device that can help a transplant patient be bridged to another transplant. ›› Learn more: Destination Therapy and the SynCardia Heart
*Source: “Cardiac Replacement with a Total Artificial Heart as a Bridge to Transplantation.” Copeland JG, Smith RG, Arabia FA, Nolan PE, Sethi GK, Tsau PH, McClellan D, and Slepian MJ. N Engl J Med 2004; 351:859-67.

INTERMACS 1 Patients & Biventricular Failure

Video: Intermacs 1 Patients and Heart Failure


Transplant Graft Failure & the SynCardia Total Artificial Heart

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