Total Artificial Heart Facts
Your heart has two ventricles that pump blood throughout the body. Deoxygenated blood is returned to the right ventricle, which pumps it through the lungs and to the left ventricle that pumps blood to the entire body. What pumps through the right ventricle must pump through the left ventricle or complications occur. The left ventricle is usually the first to fail because it works harder to pump blood to the entire body. Left ventricle failure can also mask right ventricle failure. Heart failure occurs when your heart can no longer pump enough blood to sustain your body. Vital organs like the kidneys, liver and brain are starved of the oxygen and nutrients they need to function properly.
- The SynCardia temporary Total Artificial Heart is the only device that eliminates the symptoms and source of end-stage biventricular heart failure.
- Similar to a heart transplant, the SynCardia Total Artificial Heart replaces both failing heart ventricles and the four heart valves.
- Unlike a donor heart, the Total Artificial Heart is immediately available at SynCardia Certified Centers. ›› learn more
- The Total Artificial Heart is the only device that provides immediate, safe blood flow of up to 9.5 liters per minute through each ventricle. This high volume of blood flow helps speed the recovery of vital organs, helping make the patient a better transplant candidate. ›› learn more
- The longest a patient has been supported with the SynCardia Total Artificial Heart is 1,374 days (nearly four years) prior to receiving a successful heart transplant.
- During 30 years of use, the valves in the SynCardia Total Artificial Heart have never failed. The diaphragm, which is responsible for pumping blood in and out of the ventricles, has a failure rate of less than 1% over more than 1,250 implants (2,500+ diaphragms).
- There have been more than 1,250 implants of the Total Artificial Heart, accounting for more than 350 patient years of support.
- Implanting the Total Artificial Heart eliminates the following native heart complications:
- Eliminates Arrhythmias, which may require a pacemaker and/or defibrillator. In 2009, 397,000 patients underwent pacemaker-related surgeries and 116,000 underwent surgery for an implantable defibrillator.
- Eliminates Failing ventricles, which may require medication, a left ventricular assist device (LVAD) or a right ventricular assist device (RVAD)
- Eliminates Malfunctioning heart valves, which may require surgery to correct or replace. In 2009, 139,000 patients underwent valve surgeries.
(Source: American Heart Association 2012)
- During the 10-year pivotal clinical study, approximately 65% of Total Artificial Heart patients were out of bed by the 5th day after implant.
- In addition, two weeks after implant, 60% of Total Artificial Heart patients were walking more than 100 feet.
- The Total Artificial Heart has the highest bridge to transplant rate of any approved device, 79%
According to data published in the New England Journal of Medicine1 from the 10-year pivotal clinical study which led to FDA approval, 79% of patients who received the Total Artificial Heart were bridged to transplant. This is the highest bridge to transplant rate for any approved heart device in the world.
Post-Opertive Day 5: Approximately
65% of Total Artificial Heart patients
were out of bed
Post –Operative Day 14: 60% of Total Artifical Heart Patients were walking more than 100 feet.
N Engl J Med 2004;351:859-67
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